PD 151746

Name	PD 151746
Synonyms	CS-1888 PD151746 PD 151746 PD-151746 3-(5-FLUORO-3-INDOLYL)-2-MERCAPTO-(Z)-2-PROPENOIC ACID 3-(5-fluoro-1H-indol-3-yl)-2-mercapto-2-propenoic acid PD151746 3-(5-fluoro-1H-indol-3-yl)-2-mercapto-2-Propenoic acid
CAS	179461-52-0

Molecular Formula	C11H8FNO2S
Molar Mass	237.25
Solubility	DMSO: ≥ 37 mg/mL
Appearance	powder
Color	light orange to dark orange
Storage Condition	-20°C
In vitro study	In SY5Y cells, PD151746 effectively attenuated maitotoxin-induced SLLVY-AMC hydrolysis. In HMEC-1 cells, PD 151746 attenuated oxidized low density lipoprotein (oxLDL)-induced cytotoxicity.

Safety Description	24/25 - Avoid contact with skin and eyes.
UN IDs	3077
WGK Germany	3
HS Code	29339900

Last Update：2024-01-02 23:10:35

Biological activity	PD 151746 is a selective, cell-permeable calpain inhibitor. The Ki for μ-Calpain is 2.6M, which is about 20 times higher than m-Calpain selectivity.
in vitro study	in SY5Y cells, PD151746 effectively weaken the SLLVY-AMC hydrolysis induced by maitotoxin. In HMEC-1 cells, PD 151746 attenuates oxidized low density lipoprotein (oxLDL)-induced cytotoxicity.

Last Update：2024-04-09 21:32:00

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Product Name: PD 151746 Visit Supplier Webpage Request for quotation
CAS: 179461-52-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

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PD 151746

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